SCOTTSDALE, Ariz. -- Pete Sampras faced a double whammy -- his history at the Franklin Templeton Tennis Classic and his record against Wayne Ferreira -- that he couldn't overcome Thursday night.

Ferreira beat the 13-time Grand Slam champion, who has never advanced past the second round at Scottsdale, 7-5, 7-5.

It was the South African's sixth win over Sampras in 12 meetings, six of which have gone to three sets. The victory put Ferreira into his third straight quarterfinal, this one against No. 7 Xavier Malisse on Friday.

"It's great," Ferreira said. "I've had the most success against him, and people classify him as the best tennis player. What more can I say? I can go later on in life and tell my kids and grandkids that I beat Pete Sampras six times."

The third-seeded Sampras, who plays Scottsdale because his older brother, Gus, is the tournament director, lost in the second round in 1998 and 1999, withdrew because of an injury in 2000 and dropped a first-round match to Andrew Ilie last year.

The upset deprived the tournament of a possible match between Sampras and No. 1 Andre Agassi, who plays Juan Ignacio Chela earlier Friday.

Ferreira held a 5-4 singles edge on Sampras after winning four times in a row from 1995-98. But Sampras had won the last two, including a three-set ordeal with two tiebreakers at Indian Wells in 2000.

In their first match since then, Ferreira never let Sampras get comfortable.

"I didn't have enough impact on his service game to put any pressure on him," Sampras said. "The first match I felt I kind of got going, but then maybe I played a little bit cautious, and at this level you can't afford to do that."

Ferreira got the only service breaks of the match in the 11th game of both sets, each time taking advantage of a double-fault by Sampras, who hasn't won a title since the 2000 Wimbledon.

"You have to wait for that one game that he doesn't serve aces on the first serve," Ferreira said. "Make him play on the second serve. You get blown away 95 percent of the games, but you have to wait for just that one."

Ferreira, now 9-4 in singles, bore down each time. In the 12th game of the first set, he had two service winners and finished the set with an ace while winning every point.

In the 12th game of the second, Sampras got to 30-40 with a net-skimming service return that Ferreira backhanded into the net.

But Ferreira won the next three points, ending the match with a forehand winner that passed Sampras at the net.

Malisse also has problems with Andrea Gaudenzi, taking 1 hour, 45 minutes to win 7-5, 7-6 (6).

In other matches, Rainer Schuettler beat Felix Mantilla 6-0, 2-6, 6-1 to reach his fifth quarterfinal and fourth straight, and Carlos Moya defeated Fernando Vicente 2-6, 6-2, 6-2.

Malisse got into his second quarterfinal and improved his match record to 8-4 by winning the last six points of the tiebreaker.

Down 2-6, he got even with a forehand winner, a smash, an ace and a precise groundstroke that Gaudenzi returned long.

Then Malisse made the shot of the match -- a backhand drop that landed in and spun out as Gaudenzi watched.

"I had to try it," Malisse said. "I was too tired to keep running. He had me running the whole point. I just decided to do it."

With Guadenzi serving at up to 128 mph, Malisse wasn't able to break his opponent until the 11th game of the first set.

Malisse broke again in the seventh game of the second, but Gaudenzi got the game back in the 10th.