The Most Outstanding Player of last spring's NCAA tournament was driving for the basket when she fell and took several moments to get up after getting fouled.
Boston, a 6-foot-5 senior, missed two foul shots, then ran down the floor on defense. South Carolina coach Dawn Staley subbed out Boston, who walked into the tunnel toward the locker room.
Boston rejoined her teammates on the bench midway through the third quarter with a boot on her right foot.
Staley said after the game that Boston is "questionable" for South Carolina's next matchup Tuesday against No. 20 UCLA.
"She's going to get looked at tomorrow and then we'll get some feedback from our doctor," Staley said. "Our doctor wasn't too, too concerned, but we just want to be on the safe side."
Boston -- the projected No. 1 overall pick in the upcoming WNBA draft -- has had a remarkably healthy run at South Carolina, never missing a game to date in her four-year career.
Boston is the reigning national player of the year after leading the Gamecocks' to last season's national championship.
She has averaged 13.0 points and 10.6 rebounds in South Carolina's 5-0 start this season. She had six points and four boards before leaving Sunday.
Information from ESPN's Alexa Philippou and The Associated Press was used in this report.