The 16th-ranked Blue Devils lost to the Seminoles 70-57 in Tallahassee, Florida -- the team's second ACC loss of the season.
"This would never happen in a men's game. This would never happen," she said. "It's embarrassing for our sport."
The circumference of a women's ball is about an inch smaller than a men's ball, and it is typically 2 ounces lighter. While it might not seem like a lot, that's a big difference.
Lawson said that throughout the first half, Duke players were "complaining about the ball" while going 7-for-34 from the field in the opening 20 minutes. They were 12-for-38 in the second half. Florida State made 10 of its 30 shots in the first two quarters and 14 of 31 in the second half.
"To have a game that, at the end of the season, could be the difference between a seed, between a title, my players don't deserve that and neither do their players," Lawson said. "It's a complete failure. And you can figure out who the people I'm talking about that failed the sport and our players and both teams."
Lawson said assistant coach Winston Gandy went to the scorer's table at the half to check on the ball when he realized what the problem was. She said the game officials changed the ball to start the second half.
"We have concluded through our investigation that it was a men's ball," Lawson said. "The conference and Florida State is saying that it wasn't."
The ACC said it did a comprehensive review, talking with game officials, administrators, the table crew and both schools.
"Following the thorough and objective review process, there was no evidence found to support the claim," the conference said in a statement. "Per NCAA playing rules, there is no appeal or protest process."
The ACC has instituted a procedural change that the game ball will be brought to the pregame meeting with the captains for approval.
"It's very frustrating that [the game] ... was not treated with the utmost respect that players on both teams deserve," Lawson said.
This wouldn't be the first time this has happened in women's basketball. In 2017, the College of Charleston played home games and practiced with men's balls for most of its season until the error was discovered.
"Let me be clear: Florida State beat us. They beat us playing with a men's ball in the first half and a women's ball in the second half," Lawson said. "But I can't say if we'd have played with a women's ball in the first half and the second half that we would have won. But they can't say that either."