Kafwain and jockey Victor Espinoza following the San Vincente.

Favorite Empire Maker has a bruised foot, a minor injury that could change the outlook for Saturday's race. Trainer Bobby Frankel said his star colt will still run, but the odds could change dramatically when entries are taken Wednesday.

Until the bruise on Empire Maker's right front foot was disclosed Tuesday, Churchill Downs oddsmaker Mike Battaglia was set to install Empire Maker as the strong 6-5 favorite.

"Now I'll go by what Bobby says," Battaglia said. "If he says it's nothing to worry about, he'll stay there. If he says he'll run but there are some concerns, then I'll raise the line.

"And if he says he's out, I'll have to change everything."

Baffert might be changing a few things now that Kafwain is out with a strained ligament in his right front leg following a workout. The colt won four of 11 starts and was third in the Santa Anita Derby on April 5, his last race.

That leaves Baffert, who won his third Derby with War Emblem last year, with one Derby starter -- long shot Indian Express

"At least I've got the Panamanian youth," he said, referring to Indian Express winning his first two starts in Panama.

Baffert's top Derby prospect is long gone. His 2-year-old champion Vindication was knocked off the trail in February with an injury.

The Derby Jinx appeared in Frankel's barn four days before a race that has been unkind to favorites since 1980.

Still, he was upbeat.

"You can never be 100 percent sure in this business, but I'd say I'm 98 percent sure he'll be all right," said Frankel, who also trains Derby contender Peace Rules. "But it's the Derby, you know, so what are you going to do."

After Spectacular Bid won as the .60-1 favorite in 1979, only one other favorite -- Fusaichi Pegasus at 2.30-1 in 2000 -- has returned to the winner's circle.

In 1992, favorite A.P. Indy was scratched early on race day with a bruised foot. In 1996, Unbridled's Song finished fifth as the 3.50-1 favorite after being fitted with a special shoe to protect a bruised foot.

After Empire Maker completed his final Derby workout Monday, Frankel said the most dangerous work was finished.

But on Tuesday morning, after returning from a 1-mile jog with Peace Rules, the colt's injury was discovered. That's when Frankel asked Dr. Ken Reed to take a look at Empire Maker.

"My vet doesn't think it's a problem," said the Hall of Fame trainer, looking for his first Derby win. "He recommended I walk him another day. He thinks that will take care of it."

Empire Maker moved to the head of the 3-year-old class after convincing wins in the Florida Derby and Wood Memorial. The trainer said the injury occurred following an earlier bruise to the same foot in the Wood at Aqueduct on April 12, a race run on a track drying out after a day of rain.

The bruise is under Empire Maker's shoe, part of which was filed away by a farrier so the foot could be soaked in hot water and Epsom salts. By Wednesday morning, Frankel will have a better idea of the colt's status.

With Empire Maker nicked and Kafwain out, trainer Tom Amoss said he will enter Lone Star Sky in the Derby. "After those developments, we decided to drop him in," Amoss said.

Baffert also said he will run Senor Swinger in Friday's Crown Royal American Turf. "He's not ready for the Derby," Baffert said.

The field could total 17 when entries are taken Wednesday. The tentative field includes Atswhatimtalknbout, Brancusi, Buddy Gil, Domestic Dispute, Empire Maker, Funny Cide, Indian Express, Lone Star Sky, Offlee Wild, Outta Here, Peace Rules, Scrimshaw, Sir Cherokee, Supah Blitz, Ten Cents a Shine and Ten Most Wanted.

Eye of the Tiger is still under consideration.