Kluber, who was acquired in an offseason trade with Cleveland, lasted just one inning and 18 pitches in his first start in almost 15 months. The two-time Cy Young Award winner was knocked out of his last start for the Indians on May 1, 2019, after his right forearm was broken by a comeback liner.
Finally back on the mound after his comeback attempt last year ended with an oblique injury in a rehab start, the 34-year-old Kluber struck out David Dahl to start the game. He walked Story and retired Charlie Blackmon on a popup after Story was thrown out trying to steal.
The Rangers said Kluber reported feeling the tightness in the first few pitches and it got worse as the inning progressed. He was examined by a team doctor and will be further evaluated Monday.
Texas slugger Joey Gallo hit the first home run in the club's new $1.2 billion retractable roof stadium, a 437-foot shot that almost struck a truck dealer's "Hit it Here" sign just inside the right-field foul pole.
Story, a Dallas-area native who grew up watching the Rangers across the street at the ballpark still visible through the huge windows in left field at Globe Life Field, belted a tying two-run shot in the fourth. The opposite-field drive into the first row in right came off left-hander Joe Palumbo (0-1), who replaced Kluber.
After Ryan McMahon's go-ahead sacrifice fly later in the fourth, Story drove a solo shot into the second deck in left field for a 4-2 lead in the sixth as the Rockies rallied to win the season-opening series after dropping the opener. Colorado lost its last 12 road series last season.
Colorado left-hander Kyle Freeland (1-0), who lost eight of his last nine decisions while finishing 3-11 last season, gave up two runs and four hits in six innings.
Rockies: RHP Scott Oberg (lower back strain) will throw a bullpen session Monday in Denver. Manager Bud Black said it was doubtful Oberg would be ready for the home opener July 31 against San Diego.
Rangers: Utilityman Isiah Kiner-Falefa, expected to be somewhat of a regular at third base, was out of the lineup for the second straight day with left hamstring tightness. Manager Chris Woodward said he hoped Kiner-Falefa would be ready after Monday's off day.
Both teams return Tuesday. Colorado RHP Antonio Senzatela (11-11, 6.71 ERA in 2019) is set to start in Oakland. RHP Kyle Gibson is set for his Texas debut as the Rangers' stadium-opening series continues against Arizona.
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