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What to know for NFL Week 12: Score picks, bold predictions, fantasy tips, key stats and more

What to watch for in every game. Bold predictions. Fantasy advice. Key stats to know. And, of course, final score picks. It's all here for Week 12.

Larry Radloff/Icon Sportswire

NFL Week 12 betting nuggets: Hottest favorite meets best underdog

Betting notes and trends heading into the biggest games of the weekend.

TOP HEADLINES

THANKSGIVING REACTION

How the NFL playoff picture changed on Thanksgiving: Bills retake AFC East lead

The Raiders moved a step closer to the playoffs, while the Bills jumped into the AFC East's top seed. Here is the current postseason outlook after Thursday's trio of games.

Chris Graythen/Getty Images

Takeaways: Raiders pull upset over Cowboys, Bears win on walk-off field goal, Bills roll

Here's what to know from Thanksgiving Day games.

NFL NATION

Mike Vrabel, Bill Belichick set for Round 3 as the Tennessee Titans travel to the New England Patriots

The Titans' Vrabel, who played eight seasons for Belichick with the Patriots, looks to go 3-0 against his former coach.

Brian Fluharty/USA TODAY Sports

'COME ON, MAN. WE'VE ALL BEEN THERE'

Bart Scott has no sympathy for Baker Mayfield

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FANTASY FOOTBALL

Week 12's biggest fantasy football questions: NFL reporters give advice

What should we expect from Saquon Barkley? In Derrick Henry's continued absence, is there an RB1 in Tennessee? Our reporters weigh in.

Ken Murray/Icon Sportswire

The Playbook: Your fantasy football guide to Week 12

Mike Clay provides an all-encompassing look at all of the Week 12 matchups.

Cheat Sheet: NFL Week 12 fantasy tips on players to start, sit, stream

The best fantasy football advice and information for Week 12 in the NFL from our ESPN experts, all in one spot.

NFL Playoff Machine

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  • Simulate playoff matchups

    Predict playoff pairings by selecting the winners of the remaining regular-season games to generate potential scenarios.

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