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    Houston Astros @ Cleveland Guardians

    HOU
    Houston AstrosAstrosHOU
    9-15, 2-9 Away
    CLE -149
    CLE
    Cleveland GuardiansGuardiansCLE
    13-11, 7-4 Home
    • Gamecast
    • Preview
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    Game Odds
    Odds by

    2026-04-21T22:10ZOpenMLTotalRL
    Houston AstrosAstrosHOU
    (9-15)
    (9-15, 2-9 Away)
    (9-15)
    Ryan Weiss
    (0-2, 6.75)
    o8
    -115
    +123
    o8
    -118
    +1.5
    -175
    Cleveland GuardiansGuardiansCLE
    (13-11)
    (13-11, 7-4 Away)
    (13-11)
    Parker Messick
    (3-0, 1.05)
    -149
    ML
    -149
    u8
    -102
    -1.5
    +144
    See More Odds

    Recent Schedule

    DATEOPPRESULTSPREADTOTAL
    4/20@CLEW9-2+1.57.0
    4/19vsSTLL7-5-1.59.0
    4/18vsSTLL7-5-1.59.0
    4/17vsSTLL9-4+1.59.0
    4/16vsCOLL3-2-1.58.5

    Betting 101

    The Beginner's Guide to BettingReady to enter the world of sports betting? Here's everything you need to know to get started.

    Matchup Predictor

    Houston Astros
    Cleveland Guardians
    36.2
    %
    63.8
    %

    According to ESPN Analytics

    Hitting Props

    Yordan Alvarez
    HOU LF
    Carlos Correa
    HOU SS
    Jose Altuve
    HOU LF
    Steven Kwan
    CLE LF
    Jose Ramirez
    CLE 3B
    Yainer Diaz
    HOU C
    Chase DeLauter
    CLE RF
    Isaac Paredes
    HOU 3B
    o0.5
    -265
    u0.5
    +195
    o0.5
    -258
    u0.5
    +190
    o0.5
    -244
    u0.5
    +180
    o0.5
    -225
    u0.5
    +167
    o0.5
    -227
    u0.5
    +168
    o0.5
    -202
    u0.5
    +151
    o0.5
    -194
    u0.5
    +145
    o0.5
    -190
    u0.5
    +142
    See More Odds

    More Hitting Props

    Steven Kwan
    CLE LF
    Carlos Correa
    HOU SS
    Jose Altuve
    HOU LF
    Yainer Diaz
    HOU C
    Yordan Alvarez
    HOU LF
    Christian Walker
    HOU 1B
    Isaac Paredes
    HOU 3B
    Cam Smith
    HOU RF
    o0.5
    -132
    u0.5
    -105
    o0.5
    -130
    u0.5
    -106
    o0.5
    -127
    u0.5
    -109
    o0.5
    -113
    u0.5
    -122
    o0.5
    -106
    u0.5
    -130
    o0.5
    +104
    u0.5
    -144
    o0.5
    +106
    u0.5
    -146
    o0.5
    +111
    u0.5
    -154
    See More Odds

    Pitching Props

    Parker Messick
    CLE SP
    Ryan Weiss
    HOU RP
    o5.5
    +117
    u5.5
    -149
    o3.5
    -102
    u3.5
    -125
    See More Odds

    Game Props

    Cleveland Guardians
    13-11
    Houston Astros
    9-15
    o4.5
    +110
    u4.5
    -140
    o3.5
    -120
    u3.5
    -110
    See More Odds

    Injury Report

    Houston Astros
    Name, PosStatus
    Jeremy Pena
    SS
    10-Day IL
    Zach Dezenzo
    LF
    10-Day IL
    Bennett Sousa
    RP
    15-Day IL
    Tatsuya Imai
    SP
    15-Day IL
    Joey Loperfido
    LF
    10-Day IL
    Cleveland Guardians
    Name, PosStatus
    Carlos Hernandez
    RP
    OUT
    Andrew Walters
    RP
    15-Day IL
    Gabriel Arias
    SS
    10-Day IL
    Full Injury Report
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