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    Houston Astros @ Cleveland Guardians

    HOU
    Houston AstrosAstrosHOU
    9-16, 2-10 Away
    CLE -143
    CLE
    Cleveland GuardiansGuardiansCLE
    14-11, 8-4 Home
    • Gamecast
    • Preview
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    Game Odds
    Odds by

    2026-04-22T17:10ZOpenMLTotalRL
    Houston AstrosAstrosHOU
    (9-16)
    (9-16, 2-10 Away)
    (9-16)
    Peter Lambert
    (0-1, 7.20)
    o8
    -108
    +119
    o8
    -108
    +1.5
    -181
    Cleveland GuardiansGuardiansCLE
    (14-11)
    (14-11, 8-4 Away)
    (14-11)
    Tanner Bibee
    (0-2, 4.81)
    -143
    ML
    -143
    u8
    -112
    -1.5
    +149
    See More Odds

    Recent Schedule

    DATEOPPRESULTSPREADTOTAL
    4/21@CLEL8-5+1.59.0
    4/20@CLEW9-2+1.57.0
    4/19vsSTLL7-5-1.59.0
    4/18vsSTLL7-5-1.59.0
    4/17vsSTLL9-4+1.59.0

    Betting 101

    The Beginner's Guide to BettingReady to enter the world of sports betting? Here's everything you need to know to get started.

    Matchup Predictor

    Houston Astros
    Cleveland Guardians
    46.4
    %
    53.6
    %

    According to ESPN Analytics

    Steven Kwan
    CLE LF
    Carlos Correa
    HOU SS
    Jose Altuve
    HOU LF
    Yordan Alvarez
    HOU LF
    Chase DeLauter
    CLE RF
    Jose Ramirez
    CLE 3B
    Christian Walker
    HOU 1B
    Isaac Paredes
    HOU 3B
    o0.5
    -265
    u0.5
    +195
    o0.5
    -263
    u0.5
    +194
    o0.5
    -256
    u0.5
    +188
    o0.5
    -235
    u0.5
    +174
    o0.5
    -223
    u0.5
    +166
    o0.5
    -202
    u0.5
    +151
    o0.5
    -197
    u0.5
    +147
    o0.5
    -177
    u0.5
    +133
    See More Odds
    Carlos Correa
    HOU SS
    Steven Kwan
    CLE LF
    Jose Altuve
    HOU LF
    Christian Vazquez
    HOU C
    Christian Walker
    HOU 1B
    Cam Smith
    HOU RF
    Yordan Alvarez
    HOU LF
    Chase DeLauter
    CLE RF
    o0.5
    -152
    u0.5
    +110
    o0.5
    -151
    u0.5
    +109
    o0.5
    -146
    u0.5
    +105
    o0.5
    -110
    u0.5
    -126
    o0.5
    -103
    u0.5
    -134
    o0.5
    -102
    u0.5
    -136
    o0.5
    +100
    u0.5
    -139
    o0.5
    +101
    u0.5
    -139
    See More Odds
    Tanner Bibee
    CLE SP
    Peter Lambert
    HOU RP
    o4.5
    -164
    u4.5
    +128
    o3.5
    -165
    u3.5
    +129
    See More Odds
    Cleveland Guardians
    14-11
    Houston Astros
    9-16
    o3.5
    -145
    u3.5
    +114
    o3.5
    -115
    u3.5
    -115
    See More Odds

    Injury Report

    Houston Astros
    Name, PosStatus
    Dustin Harris
    LF
    Day-To-Day
    Jeremy Pena
    SS
    10-Day IL
    Zach Dezenzo
    LF
    10-Day IL
    Bennett Sousa
    RP
    15-Day IL
    Tatsuya Imai
    SP
    15-Day IL
    Cleveland Guardians
    Name, PosStatus
    Carlos Hernandez
    RP
    OUT
    Andrew Walters
    RP
    15-Day IL
    Gabriel Arias
    SS
    10-Day IL
    Full Injury Report
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