Check out the full fixture list for the 2021-22 Premier League season.
West Ham United secured Europa League football for next season and their best ever Premier League points total after beating Southampton.
Manchester United are still looking to sign another striker and could turn to Southampton's Danny Ings. Transfer Talk has the latest.
Leeds United's Patrick Bamford and Tyler Roberts scored late on to spoil the party for Southampton fans as the visitors claimed a 2-0 victory.
Nathan Tella scored one goal and made another as Southampton secured a 3-1 home win over Fulham to pile more misery for the already-relegated team.
Danny Ings scored twice on his return from injury to help Southampton bounce back for a Premier League win over Crystal Palace on Tuesday.
Liverpool rode a Sadio Mane opener and some heroics from goalkeeper Alisson to a win over Southampton at Anfield on Saturday.
Third-placed Leicester City suffered a frustrating night on the south coast as they were held to a 1-1 draw by Southampton.
Second-half strikes from Son Heung-min and Gareth Bale handed Tottenham Hotspur a Premier League win over Southampton on Wednesday night.
Kelechi Iheanacho scored the game's only goal as Leicester City saw out a narrow victory over Southampton to book a spot in the FA Cup final.
After Chelsea shocked Manchester City 1-0 on Saturday, it's down to Leicester and Southampton to battle it out for other berth in the FA Cup final.
West Brom beat Southampton 3-0 in convincing fashion in the Premier League on Monday as they look to salvage their top flight survival hopes.
Southampton fought back from two goals down to beat Burnley 3-2 in the Premier League on Sunday and increase their comfort above the relegation zone
Manchester City are set to bid for Southampton top scorer Danny Ings as Sergio Aguero's contract ends. Transfer Talk is LIVE with the latest.
Manchester City, who are chasing silverware on four fronts, have been drawn against Chelsea in the pick of the FA Cup semifinals.
Nathan Redmond netted twice and Moussa Djenepo also scored as Southampton beat Bournemouth to book their place in the FA Cup semifinals.
Brighton & Hove Albion secured their first Premier League win over Southampton as goals from Lewis Dunk and Leandro Trossard led them to a 2-1 win.
Manchester City were back to winning ways in the Premier League with a 5-2 victory over Southampton at the Etihad Stadium on Wednesday.
Pep Guardiola has dismissed a suggestion that Manchester City could hand Southampton another 9-0 thrashing, he said "the score will be 18-0."
Southampton claimed their first Premier League victory in 10 games as James Ward-Prowse and Che Adam saw off Sheffield Utd.
Richarlison's early goal for Everton secured a 1-0 Premier League win over ailing Southampton on Monday to compound the woes for the visitors.
Southampton midfielder Oriol Romeu has been ruled out for the remainder of the season with an ankle injury which will need surgery, manager Ralph Ha
|Brighton & Hove Albion||0||0||0||0||0||0|
|West Ham United||0||0||0||0||0||0|