Zlatan Ibrahimovic missed another penalty, the third in his last five attempts, as AC Milan cruised past Sparta Prague 3-0 in the Europa League.
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Struggling Sparta Prague have fired Andrea Stramaccioni as coach despite spending big on new players.
Tomas Rosicky has retired from professional football, Sparta Prague have announced.
The Cameroon midfielder has left Metz after two seasons for a new challenge in the Czech Republic.
Austria striker Marc Janko has moved to Sparta Prague on a two-year contract.
Italian, who has signed a two-year deal, becomes just the fourth foreign coach in the Czech Republic's top division.
Former Czech Republic captain Tomas Rosicky had an operation on an Achilles tendon on Monday and won't play for the rest of the season.
Athletic Bilbao crashed out of the Europa League in the round of 32 on Thursday with a 2-0 defeat at APOEL, falling 4-3 on aggregate.
Zlatan Ibrahimovic's hat trick gave Manchester United a 3-0 win against St Etienne in a Europa League round of 32 first-leg clash at Old Trafford.
Manchester United will take on St Etienne in the Europa League's round of 32, while Spurs will face Gent and Villarreal have been drawn against Roma.
Police say 12 Sparta Prague fans were arrested for clashes during a Europa League match at Inter Milan.
Claude Puel has told his Southampton players not to be too downbeat after their 1-0 Europa League defeat at Sparta Prague.
Southampton's hopes of reaching the Europa League's knockout stages have been left in the balance after a 1-0 defeat at Sparta Prague.
Tomas Rosicky is still injured and unlikely to play for Sparta Prague until the spring of 2017.
Manchester United's troubles away from home in Europe continued in a 2-1 defeat at Fenerbahce in the Europa League as Paul Pogba limped off injured.
Sparta Prague have told two of their players to train with the club's women's team after making "unacceptable" comments about a female match official
Sparta Prague goalkeeper Tomas Koubek has apologised for his outburst against women after a female referee's assistant failed to call offside.
Manchester United laboured to a 1-0 Europa League victory over Zorya Luhansk at Old Trafford as Zlatan Ibrahimovic headed home in the second half.
Southampton made a winning start to their Europa League campaign and gave Claude Puel his first win as manager with a 3-0 defeat of Sparta Prague.
Thousands welcomed Tomas Rosicky in his highly anticipated return to Sparta Prague and the Czech league after more than 15 years away.
Sparta announced the move on Tuesday, with details of the transfer due to be announced at a news conference later in the day.
Shakhtar Donetsk, Olympiakos and Fenerbahce all crashed out of the UEFA Champions League in the third qualifying round on Wednesday.
Shakhtar Donetsk began their Champions League campaign with a 2-0 win over Young Boys in the third qualifying round on Tuesday.