HoustonAstros
- 78-80
- 2nd in AL West
Houston Astros Schedule 2021
| DATE | OPPONENT | RESULT | W-L | WIN | LOSS | SAVE | ATT |
| Fri, Jul 16 | W7-1 | 56-36 | McCullers Jr. 7-2 | Cease 7-5 | 34,516 | ||
| Sat, Jul 17 | L10-1 | 56-37 | Giolito 8-6 | Odorizzi 3-5 | 34,304 | ||
| Sun, Jul 18 | L4-0 | 56-38 | Rodon 8-3 | Valdez 5-2 | 34,148 | ||
| Mon, Jul 19 | W4-3 | 57-38 | Greinke 9-3 | Mejia 1-5 | Pressly 17 | 21,963 | |
| Tue, Jul 20 | W9-3 | 58-38 | Garcia 7-5 | McKenzie 1-4 | 26,586 | ||
| Wed, Jul 21 | L5-4 | 58-39 | Shaw 3-3 | Pruitt 0-1 | Karinchak 11 | 21,712 | |
| Fri, Jul 23 | W7-3 | 59-39 | Bielak 3-3 | Allard 2-8 | 38,853 | ||
| Sat, Jul 24 | W4-1 | 60-39 | Valdez 6-2 | Gibson 6-3 | 37,050 | ||
| Sun, Jul 25 | W3-1 | 61-39 | Greinke 10-3 | Santana 0-1 | Pressly 18 | 35,627 | |
| Mon, Jul 26 | L11-8 | 61-40 | Graveman 4-0 | Stanek 1-2 | Sewald 4 | 15,162 | |
| Tue, Jul 27 | W8-6 | 62-40 | McCullers Jr. 8-2 | Flexen 9-5 | 18,930 | ||
| Wed, Jul 28 | W11-4 | 63-40 | Odorizzi 4-5 | Kikuchi 6-6 | 18,908 | ||
| Fri, Jul 30 | W9-6 | 64-40 | Valdez 7-2 | Gausman 9-5 | 28,020 | ||
| Sat, Jul 31 | L8-6 | 64-41 | Jackson 2-0 | Taylor 2-3 | McGee 22 | 27,324 | |
| Sun, Aug 1 | L5-3 | 64-42 | Webb 5-3 | Garcia 7-6 | McGee 23 | 29,655 | |
| Tue, Aug 3 | W3-0 | 65-42 | McCullers Jr. 9-2 | Buehler 11-2 | Stanek 2 | 52,692 | |
| Wed, Aug 4 | L7-5 | 65-43 | Scherzer 9-4 | Odorizzi 4-6 | 52,724 | ||
| Thu, Aug 5 | L5-3 | 65-44 | Jax 2-1 | Valdez 7-3 | Colome 4 | 26,208 | |
| Fri, Aug 6 | L5-4 F/11 | 65-45 | Minaya 2-0 | Montero 5-4 | 29,631 | ||
| Sat, Aug 7 | W4-0 | 66-45 | Garcia 8-6 | Pineda 4-7 | 29,647 | ||
| Sun, Aug 8 | L7-5 | 66-46 | Maeda 5-4 | McCullers Jr. 9-3 | Colome 5 | 26,825 | |
| Tue, Aug 10 | W5-0 | 67-46 | Odorizzi 5-6 | Gray 7-8 | 28,931 | ||
| Wed, Aug 11 | W5-1 | 68-46 | Valdez 8-3 | Senzatela 2-9 | 22,200 | ||
| Fri, Aug 13 | W4-1 | 69-46 | Greinke 11-3 | Sandoval 3-6 | Pressly 19 | 23,981 | |
| Sat, Aug 14 | W8-2 | 70-46 | Garcia 9-6 | Barria 2-1 | 27,121 | ||
| Sun, Aug 15 | L3-1 | 70-47 | Detmers 1-2 | McCullers Jr. 9-4 | Iglesias 26 | 19,281 | |
| Mon, Aug 16 | L7-6 | 70-48 | Barlow 5-3 | Garcia 3-8 | 10,228 | ||
| Tue, Aug 17 | L3-1 | 70-49 | Lynch IV 3-3 | Valdez 8-4 | Brentz 2 | 9,748 | |
| Wed, Aug 18 | L3-2 | 70-50 | Tapia 1-0 | Taylor 2-4 | Barlow 7 | 12,278 | |
| Thu, Aug 19 | W6-3 F/10 | 71-50 | Pressly 5-1 | Davis 0-3 | Javier 2 | 9,884 | |
| Fri, Aug 20 | W12-3 | 72-50 | McCullers Jr. 10-4 | Kikuchi 7-7 | 26,899 | ||
| Sat, Aug 21 | W15-1 | 73-50 | Odorizzi 6-6 | Gilbert 5-5 | 29,908 | ||
| Sun, Aug 22 | L6-3 F/11 | 73-51 | Sewald 8-3 | Stanek 1-3 | Ramirez 1 | 27,526 | |
| Mon, Aug 23 | L7-1 | 73-52 | Lynch IV 4-3 | Greinke 11-4 | 18,742 | ||
| Tue, Aug 24 | W4-0 | 74-52 | Garcia 10-6 | Singer 3-9 | 22,964 | ||
| Wed, Aug 25 | W6-5 F/10 | 75-52 | Graveman 5-0 | Payamps 0-3 | 21,052 | ||
| Fri, Aug 27 | W5-4 | 76-52 | Maton 3-0 | Martin 3-4 | Pressly 20 | 29,286 | |
| Sat, Aug 28 | W5-2 | 77-52 | Valdez 9-4 | Allard 3-11 | Pressly 21 | 37,810 | |
| Sun, Aug 29 | L13-2 | 77-53 | Hearn 4-4 | Greinke 11-5 | 31,062 | ||
| Mon, Aug 30 | W4-3 | 78-53 | Maton 4-0 | Smith 2-3 | Pressly 22 | 11,630 | |
| Tue, Aug 31 | L4-0 | 78-54 | Sewald 9-3 | Graveman 5-1 | 10,452 | ||
| Wed, Sep 1 | L1-0 | 78-55 | Sheffield 6-8 | Odorizzi 6-7 | Sewald 8 | 10,519 | |
| Fri, Sep 3 | W6-3 | 79-55 | Taylor 3-4 | Pagan 4-1 | Pressly 23 | 37,033 | |
| Sat, Sep 4 | L10-2 | 79-56 | Musgrove 10-8 | Valdez 9-5 | 35,338 | ||
| Sun, Sep 5 | L4-3 | 79-57 | Melancon 4-2 | Stanek 1-4 | 35,007 | ||
| Mon, Sep 6 | W11-2 | 80-57 | McCullers Jr. 11-4 | Kikuchi 7-8 | Bielak 1 | 25,802 | |
| Tue, Sep 7 | W5-4 F/10 | 81-57 | Stanek 2-4 | Ramirez 1-3 | 20,353 | ||
| Wed, Sep 8 | L8-5 | 81-58 | Castillo 3-5 | Pressly 5-2 | 19,089 | ||
| Fri, Sep 10 | W10-5 | 82-58 | Valdez 10-5 | Ohtani 9-2 | 28,740 | ||
| Sat, Sep 11 | L4-2 | 82-59 | Suarez 7-7 | Garcia 10-7 | Iglesias 31 | 31,547 | |
| Sun, Sep 12 | W3-1 | 83-59 | McCullers Jr. 12-4 | Quijada 0-1 | Pressly 24 | 28,763 | |
| Mon, Sep 13 | W15-1 | 84-59 | Javier 4-1 | Howard 0-4 | 18,903 | ||
| Tue, Sep 14 | L8-1 | 84-60 | Lyles 9-11 | Greinke 11-6 | 19,451 | ||
| Wed, Sep 15 | W7-2 | 85-60 | Urquidy 7-3 | Arihara 2-4 | 20,991 | ||
| Thu, Sep 16 | W12-1 | 86-60 | Garcia 11-7 | Otto 0-2 | 19,121 | ||
| Fri, Sep 17 | W4-3 F/10 | 87-60 | Stanek 3-4 | Clippard 1-1 | 22,595 | ||
| Sat, Sep 18 | L6-4 F/10 | 87-61 | Wendelken 3-2 | Garcia 3-9 | Clippard 6 | 25,314 | |
| Sun, Sep 19 | W7-6 | 88-61 | Solomon 1-0 | Sittinger 0-1 | Pressly 25 | 23,888 | |
| Mon, Sep 20 | W10-0 | 89-61 | Valdez 11-5 | Barria 2-4 | 16,070 | ||
| Tue, Sep 21 | W10-5 | 90-61 | Urquidy 8-3 | Naughton 0-3 | 18,332 | ||
| Wed, Sep 22 | W9-5 F/12 | 91-61 | Garcia 4-9 | Selman 0-1 | 14,863 | ||
| Thu, Sep 23 | L3-2 | 91-62 | Warren 2-0 | McCullers Jr. 12-5 | Iglesias 33 | 19,829 | |
| Fri, Sep 24 | L14-2 | 91-63 | Montas 13-9 | Bielak 3-4 | 21,105 | ||
| Sat, Sep 25 | L2-1 | 91-64 | Chafin 2-3 | Pressly 5-3 | 13,037 | ||
| Sun, Sep 26 | L4-3 | 91-65 | Trivino 7-7 | Stanek 3-5 | 12,288 | ||
| Tue, Sep 28 | W4-3 | 92-65 | Maton 5-0 | Fleming 10-7 | 32,297 | ||
| Wed, Sep 29 | L7-0 | 92-66 | Rasmussen 4-1 | Garcia 11-8 | 28,321 | ||
| Thu, Sep 30 | W3-2 | 93-66 | McCullers Jr. 13-5 | Yarbrough 9-7 | Pressly 26 | 31,608 | |
| Fri, Oct 1 | L8-6 | 93-67 | Manaea 11-10 | Valdez 11-6 | Trivino 22 | 26,762 | |
| Sat, Oct 2 | W10-4 | 94-67 | Maton 6-0 | Blackburn 1-4 | 29,208 | ||
| Sun, Oct 3 | W7-6 | 95-67 | Taylor 4-4 | Trivino 7-8 | 29,752 |