After a recent absence because of the flu, Ramirez doubled during a three-run rally in the eighth inning Thursday that sent the Red Sox over the Pittsburgh Pirates 4-3.
"I think he's carried what he did last year into this season despite missing the four games in Detroit," Red Sox manager John Farrell said. "I think he's carried that confidence he had last season into the first five games that he's been active."
The game was a makeup from a rainout in the opening series. Boston wound up sweeping the Pirates, having beaten them in the first two games of the year.
Ramirez got his first RBI of the season, hitting a two-run double with the bases loaded off Juan Nicasio (0-2) that made it 3-all. Mookie Betts, the second of two close runners heading home, was out at the plate.
Xander Bogaerts then slapped a go-ahead single to right.
"My pitch was just to throw a sinker inside and I didn't miss," Nicasio said. "The thing is Hanley came out on top."
"Being at this ballpark and knowing you've got a little help in left there makes you feel little more comfortable," Moreland said of the Green Monster.
McCutchen hit the first pitch he saw from Eduardo Rodriguez off a billboard above the Monster for his 176th career homer.
The 30-year-old McCutchen -- the NL's 2013 MVP -- entered the day with just one RBI following an offseason filled with trade rumors.
Pittsburgh starter Chad Kuhl gave up one run on five hits over 6 1/3 innings, striking out six without a walk.
"Chad pitched a fantastic game," Pirates manager Clint Hurdle said. "To hold that offense in check, to pitch into the seventh, no walks, six strikeouts, the fastball command was excellent."
Rodriguez gave up two of his three runs in the first inning, but struck out eight with four walks over 5 1/3.
Pirates: They may be a bit tired after a quick trip in and out of Boston. They arrived just before 1 a.m. and were heading to Chicago for a weekend series against the Cubs.
Red Sox: Ace lefty David Price, out since early into spring training with a strained left elbow, is set to throw a bullpen session on Saturday. ... Farrell gave struggling 3B Pablo Sandoval the day off. He's hitting just .133 (4 for 30) with two homers and seven RBI. ... LHP Robbie Ross Jr. was removed from his rehab assignment at Triple-A Pawtucket and activated from the 10-day disabled list. He was out with the flu. To make room, RHP Ben Taylor was optioned to Pawtucket.
MAKING IT LOOK EASY
Pirates third baseman Josh Harrison made a nice over-the-shoulder grab on a foul pop near the seats for the first out of the fifth and closed the inning by catching one down the third base line close to the stands.
Pirates: RHP Gerrit Cole (0-1, 6.55 ERA) is set to start against RHP Kyle Hendricks (1-0, 6.00) Friday afternoon in the first of three day games in Chicago. The Pirates were 1-8 at Wrigley Field last season, but Cole is 8-2 in his career against the Cubs.
Red Sox: They open a four-game series Friday against Tampa Bay with reigning AL Cy Young Award winner Rick Porcello (1-0, 4.38) facing Rays RHP Chris Archer (1-0, 2.45). Porcello has gone at least six innings in 20 consecutive starts, the majors' longest active streak.
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