The heavyweight championship is on the line at UFC 334 on Saturday night when Ciryl Gane makes his first defence against Josh Hokit.
Britain's Tom Aspinall gave up the title earlier this year as he continues his difficult recovery from an eye injury caused by Gane. France's Gane won the interim belt, with Aspinall sidelined, at the White House by stopping Alex Pereira and has since been elevated to the status of full champion.
Elsewhere at UFC 334, there is a sensational scrap between Kayla Harrison and Amanda Nunes.
Here's everything that fans in the UK need to know about UFC 334.
When and where is UFC 334? What is UFC 334 start time?
UFC 334 is at Madison Square Garden in New York City on Saturday, Nov. 14.
The early prelims will begin at 10 p.m. GMT before the regular prelims begin at midnight GMT. The main card will begin at 2 a.m. GMT in the early hours of Sunday, Nov. 15.
How to watch UFC 334 in the UK
UFC 334 is on TNT Sports, and its streaming partner HBO Max, in the UK.
What's at stake at UFC 334?
The UFC heavyweight title is at stake when Gane (14-2) fights Hokit (10-0) in the main-event.
Gane -- who, uniquely, has fought Jon Jones, Aspinall, Francis Ngannou and Pereira -- was elevated to becoming full champion due to Aspinall's injury. So defending his belt will finally solidify him as the UFC's No. 1 heavyweight if any doubters remain.
Hokit is undefeated in 10 fights and represents an intriguing new challenge. His outspoken, brash, WWE-style persona has courted attention and controversy. It has also shone a light on his fighting -- he responded with impressive wins over Curtis Blaydes and Derrick Lewis.
This fight will also have repurcussions for the sidelined Aspinall who will hope to re-enter the title picture.
The women's bantamweight title is up for grabs as Nunes (23-5) comes out of retirement to challenge Harrison (19-1).
Nunes is a former two-division champion and one of the best female MMA fighters ever. Now 38, she hasn't fought in three years. A previously scheduled fight against Harrison was cancelled due to a neck injury for the champion.
Harrison, who has impressed since transitioning to MMA after winning two Olympic gold medals in judo, won the title in her last fight.
Harrison vs. Nunes is also deeply personal. Former training partners, both fighters have made it clear that there is no love lost.
UFC 334 main card
Ciryl Gane vs. Josh Hokit
Kayla Harrison vs. Amanda Nunes
Caio Borralho vs. Yousri Belgaroui
Uros Medic vs. Kevin Holland
Bilal Hasan vs. Luis Gurule
Prelims
Stephen Thompson vs. Charles Radtke
Drew Dober vs. Chris Duncan
Jim Miller vs. Terrance McKinney