| MLB - Pitching - RP - ESPN Player Rating | ||||||||||||||
| RK | PLAYER | TEAM | IP | W | L | SV | BS | K | BB | HBP | BAA | HR | ERA | RAT |
| 1 | Mason Miller | SD | 18.0 | 1 | 0 | 12 | 0 | 38 | 5 | 0 | .111 | 0 | 0.96 | 50.3 |
| 2 | Riley O'Brien | STL | 18.0 | 3 | 1 | 11 | 2 | 20 | 1 | 2 | .224 | 0 | 2.00 | 32.9 |
| 3 | Aroldis Chapman | BOS | 12.0 | 0 | 1 | 8 | 0 | 16 | 3 | 1 | .163 | 0 | 0.71 | 32.7 |
| 4 | Robert Suarez | ATL | 15.0 | 3 | 0 | 4 | 0 | 16 | 2 | 0 | .211 | 0 | 0.57 | 29.0 |
| 5 | Dylan Lee | ATL | 18.0 | 1 | 0 | 0 | 1 | 23 | 2 | 0 | .113 | 0 | 0.96 | 28.1 |
| 6 | Cade Smith | CLE | 18.0 | 2 | 0 | 11 | 2 | 24 | 4 | 0 | .268 | 1 | 3.44 | 27.8 |
| 7 | Paul Sewald | ARI | 13.0 | 0 | 3 | 8 | 0 | 17 | 4 | 0 | .130 | 3 | 3.29 | 25.1 |
| 8 | Bryan Baker | TB | 14.0 | 1 | 0 | 9 | 2 | 16 | 3 | 0 | .170 | 1 | 2.45 | 24.2 |
| 9 | Louis Varland | TOR | 19.0 | 1 | 1 | 5 | 0 | 29 | 7 | 0 | .206 | 0 | 0.46 | 23.7 |
| 10 | Rico Garcia | BAL | 17.0 | 3 | 0 | 2 | 1 | 19 | 6 | 0 | .020 | 1 | 0.53 | 23.3 |
| 11 | John King | MIA | 16.0 | 1 | 0 | 1 | 0 | 15 | 6 | 2 | .059 | 1 | 0.54 | 21.9 |
| 12 | Jacob Latz | TEX | 18.0 | 0 | 1 | 3 | 1 | 16 | 4 | 0 | .081 | 1 | 0.96 | 21.9 |
| 13 | Gregory Soto | PIT | 19.0 | 3 | 0 | 3 | 1 | 25 | 7 | 1 | .097 | 1 | 1.42 | 21.6 |
| 14 | David Bednar | NYY | 16.0 | 1 | 2 | 10 | 1 | 19 | 5 | 1 | .269 | 0 | 3.31 | 21.0 |
| 15 | Seranthony Dominguez | CHW | 14.0 | 2 | 3 | 8 | 2 | 19 | 9 | 2 | .157 | 3 | 3.68 | 20.0 |
| 16 | Antonio Senzatela | COL | 24.0 | 2 | 0 | 2 | 0 | 22 | 7 | 0 | .159 | 0 | 1.11 | 19.7 |
| 17 | Tanner Scott | LAD | 16.0 | 0 | 1 | 3 | 0 | 16 | 2 | 0 | .143 | 2 | 1.65 | 19.2 |
| 18 | Yennier Cano | BAL | 14.0 | 1 | 1 | 0 | 0 | 11 | 1 | 0 | .125 | 1 | 1.29 | 19.2 |
| 19 | Lucas Erceg | KC | 16.0 | 3 | 1 | 10 | 2 | 14 | 12 | 0 | .200 | 0 | 3.31 | 19.2 |
| 20 | Daniel Lynch IV | KC | 15.0 | 1 | 0 | 1 | 1 | 20 | 4 | 2 | .094 | 1 | 1.72 | 16.7 |
| 21 | Jakob Junis | TEX | 16.0 | 0 | 0 | 3 | 0 | 7 | 5 | 2 | .143 | 0 | 1.65 | 13.8 |
| 22 | Juan Morillo | ARI | 18.0 | 1 | 1 | 1 | 1 | 21 | 4 | 1 | .143 | 1 | 2.00 | 12.6 |
| 23 | Andres Munoz | SEA | 15.0 | 3 | 3 | 7 | 2 | 25 | 7 | 0 | .241 | 3 | 6.00 | 12.5 |
| 24 | Gordon Graceffo | STL | 20.0 | 2 | 0 | 1 | 0 | 10 | 7 | 2 | .162 | 1 | 1.74 | 12.2 |
| 25 | Ben Brown | CHC | 29.0 | 1 | 1 | 1 | 1 | 27 | 9 | 0 | .175 | 1 | 1.82 | 12.0 |
| 26 | Alex Vesia | LAD | 13.0 | 1 | 0 | 2 | 0 | 16 | 6 | 0 | .093 | 0 | 1.38 | 11.7 |
| 27 | Tyler Samaniego | BOS | 13.0 | 0 | 0 | 0 | 0 | 11 | 6 | 1 | .174 | 0 | 0.00 | 11.6 |
| 28 | Tyler Phillips | MIA | 23.0 | 0 | 0 | 2 | 1 | 24 | 13 | 1 | .205 | 1 | 1.14 | 11.4 |
| 29 | Brooks Raley | NYM | 15.0 | 0 | 1 | 0 | 0 | 18 | 5 | 0 | .157 | 1 | 1.20 | 11.3 |
| 30 | Matt Gage | SF | 16.0 | 2 | 1 | 0 | 0 | 10 | 10 | 0 | .170 | 1 | 1.13 | 10.8 |
| 31 | DL Hall | MIL | 18.0 | 0 | 0 | 0 | 0 | 21 | 12 | 1 | .148 | 1 | 1.50 | 10.7 |
| 32 | Caleb Kilian | SF | 17.0 | 1 | 1 | 1 | 0 | 18 | 10 | 1 | .155 | 2 | 1.59 | 10.7 |
| 33 | Jose Ferrer | SEA | 19.0 | 0 | 1 | 2 | 1 | 16 | 3 | 2 | .299 | 0 | 1.89 | 10.5 |
| 34 | Devin Williams | NYM | 12.0 | 2 | 1 | 5 | 1 | 21 | 6 | 0 | .294 | 1 | 5.68 | 10.1 |
| 35 | Hunter Bigge | TB | 13.0 | 1 | 0 | 0 | 0 | 11 | 8 | 0 | .111 | 1 | 2.77 | 9.9 |
| 36 | Brent Headrick | NYY | 21.0 | 3 | 0 | 0 | 0 | 22 | 8 | 0 | .234 | 1 | 1.71 | 9.8 |
| 37 | Brant Hurter | DET | 20.0 | 4 | 1 | 0 | 0 | 14 | 5 | 1 | .171 | 1 | 1.77 | 9.6 |
| 38 | Scott Barlow | ATH | 18.0 | 0 | 0 | 0 | 1 | 17 | 9 | 4 | .115 | 2 | 3.38 | 9.5 |
| 39 | Grant Wolfram | BAL | 13.0 | 1 | 1 | 0 | 0 | 20 | 1 | 3 | .328 | 0 | 4.85 | 9.3 |
| 40 | Erik Sabrowski | CLE | 17.0 | 1 | 1 | 0 | 0 | 29 | 7 | 0 | .121 | 1 | 2.08 | 8.7 |
| 41 | Joel Kuhnel | ATH | 14.0 | 0 | 1 | 4 | 0 | 5 | 4 | 0 | .204 | 0 | 1.84 | 8.4 |
| 42 | Colin Holderman | CLE | 13.0 | 0 | 0 | 0 | 0 | 14 | 3 | 0 | .125 | 1 | 1.32 | 8.4 |
| 43 | Bryan Hudson | CHW | 18.0 | 0 | 0 | 1 | 1 | 21 | 9 | 1 | .254 | 0 | 1.00 | 8.4 |
| 44 | Keaton Winn | SF | 16.0 | 0 | 1 | 0 | 0 | 14 | 6 | 0 | .132 | 0 | 2.76 | 8.4 |
| 45 | Brad Keller | PHI | 16.0 | 1 | 1 | 3 | 0 | 18 | 6 | 1 | .250 | 2 | 4.32 | 7.2 |
| 46 | Tim Hill | NYY | 16.0 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | .193 | 1 | 1.10 | 7.2 |
| 47 | Kyle Finnegan | DET | 17.0 | 1 | 0 | 1 | 1 | 13 | 13 | 0 | .213 | 1 | 1.53 | 7.1 |
| 48 | Lake Bachar | MIA | 19.0 | 0 | 0 | 0 | 0 | 22 | 7 | 1 | .141 | 2 | 2.37 | 7.1 |
| 49 | Paxton Schultz | WSH | 13.0 | 0 | 0 | 1 | 1 | 12 | 2 | 1 | .231 | 2 | 2.77 | 6.8 |
| 50 | Eduard Bazardo | SEA | 17.0 | 2 | 1 | 0 | 1 | 13 | 5 | 0 | .242 | 0 | 1.53 | 6.6 |