| MLB - Pitching - SP - ESPN Player Rating | ||||||||||||||
| RK | PLAYER | TEAM | IP | W | L | SV | BS | K | BB | HBP | BAA | HR | ERA | RAT |
| 1 | Cam Schlittler | NYY | 66.0 | 6 | 2 | 0 | 0 | 75 | 13 | 0 | .185 | 2 | 1.50 | 70.8 |
| 2 | Cristopher Sanchez | PHI | 64.0 | 5 | 2 | 0 | 0 | 80 | 14 | 1 | .251 | 3 | 1.82 | 60.2 |
| 3 | Chase Burns | CIN | 59.0 | 6 | 1 | 0 | 0 | 64 | 18 | 0 | .183 | 7 | 1.83 | 57.8 |
| 4 | Davis Martin | CHW | 56.0 | 6 | 1 | 0 | 0 | 59 | 10 | 3 | .223 | 3 | 1.61 | 54.2 |
| 5 | Jose Soriano | LAA | 59.0 | 6 | 3 | 0 | 0 | 67 | 26 | 1 | .181 | 5 | 2.41 | 53.0 |
| 6 | Jacob Misiorowski | MIL | 57.0 | 4 | 2 | 0 | 0 | 88 | 18 | 5 | .160 | 4 | 1.89 | 49.8 |
| 7 | Chris Sale | ATL | 62.0 | 7 | 3 | 0 | 0 | 72 | 14 | 5 | .181 | 6 | 1.89 | 49.3 |
| 8 | Paul Skenes | PIT | 55.0 | 6 | 3 | 0 | 0 | 63 | 8 | 4 | .161 | 5 | 2.62 | 46.9 |
| 9 | Parker Messick | CLE | 58.0 | 5 | 1 | 0 | 0 | 64 | 17 | 1 | .208 | 6 | 2.45 | 46.1 |
| 10 | Bryce Elder | ATL | 62.0 | 4 | 2 | 0 | 0 | 56 | 20 | 2 | .187 | 4 | 2.01 | 44.4 |
| 11 | Nick Martinez | TB | 53.0 | 4 | 1 | 0 | 0 | 35 | 11 | 2 | .224 | 3 | 1.51 | 43.4 |
| 12 | Spencer Arrighetti | HOU | 36.0 | 5 | 1 | 0 | 0 | 35 | 21 | 4 | .176 | 1 | 1.50 | 40.8 |
| 13 | Justin Wrobleski | LAD | 50.0 | 6 | 1 | 0 | 0 | 27 | 12 | 2 | .212 | 2 | 2.49 | 40.5 |
| 14 | Michael King | SD | 58.0 | 4 | 2 | 0 | 0 | 59 | 24 | 4 | .191 | 4 | 2.31 | 40.1 |
| 15 | Max Meyer | MIA | 53.0 | 4 | 0 | 0 | 0 | 60 | 19 | 3 | .203 | 4 | 2.85 | 31.2 |
| 16 | Randy Vasquez | SD | 54.0 | 5 | 2 | 0 | 0 | 45 | 16 | 3 | .244 | 5 | 2.96 | 31.2 |
| 17 | Michael Wacha | KC | 63.0 | 4 | 2 | 0 | 0 | 55 | 20 | 3 | .200 | 7 | 2.70 | 31.1 |
| 18 | Max Fried | NYY | 61.0 | 4 | 3 | 0 | 0 | 50 | 19 | 2 | .199 | 1 | 3.21 | 31.1 |
| 19 | Shane McClanahan | TB | 44.0 | 5 | 2 | 0 | 0 | 47 | 17 | 0 | .183 | 2 | 2.82 | 30.8 |
| 20 | Eduardo Rodriguez | ARI | 53.0 | 4 | 1 | 0 | 0 | 39 | 22 | 0 | .224 | 4 | 2.53 | 30.2 |
| 21 | Aaron Civale | ATH | 51.0 | 5 | 1 | 0 | 0 | 37 | 16 | 1 | .276 | 9 | 3.31 | 29.4 |
| 22 | Dylan Cease | TOR | 57.0 | 3 | 2 | 0 | 0 | 84 | 25 | 3 | .214 | 3 | 2.98 | 28.4 |
| 23 | Michael McGreevy | STL | 56.0 | 3 | 3 | 0 | 0 | 37 | 12 | 0 | .215 | 7 | 2.40 | 27.7 |
| 24 | Kyle Harrison | MIL | 45.0 | 5 | 1 | 0 | 0 | 59 | 14 | 3 | .211 | 3 | 1.77 | 26.9 |
| 25 | Ranger Suarez | BOS | 48.0 | 2 | 2 | 0 | 0 | 43 | 14 | 0 | .202 | 3 | 2.40 | 26.7 |
| 26 | Clay Holmes | NYM | 52.0 | 4 | 4 | 0 | 0 | 45 | 18 | 1 | .206 | 3 | 2.39 | 26.0 |
| 27 | Gavin Williams | CLE | 61.0 | 6 | 3 | 0 | 0 | 73 | 22 | 1 | .225 | 9 | 3.67 | 24.5 |
| 28 | Tyler Glasnow | LAD | 39.0 | 3 | 0 | 0 | 0 | 49 | 13 | 0 | .149 | 5 | 2.72 | 23.7 |
| 29 | Landen Roupp | SF | 55.0 | 5 | 4 | 0 | 0 | 61 | 21 | 2 | .210 | 2 | 3.27 | 22.1 |
| 30 | Tarik Skubal | DET | 43.0 | 3 | 2 | 0 | 0 | 45 | 6 | 1 | .222 | 2 | 2.70 | 21.7 |
| 31 | Sonny Gray | BOS | 40.0 | 5 | 1 | 0 | 0 | 30 | 9 | 2 | .237 | 4 | 2.93 | 21.0 |
| 32 | Taj Bradley | MIN | 47.0 | 4 | 1 | 0 | 0 | 52 | 17 | 2 | .219 | 5 | 2.87 | 20.9 |
| 33 | Casey Mize | DET | 37.0 | 2 | 2 | 0 | 0 | 39 | 11 | 1 | .211 | 2 | 2.43 | 19.5 |
| 34 | Will Warren | NYY | 52.0 | 6 | 1 | 0 | 0 | 62 | 13 | 1 | .240 | 6 | 3.61 | 19.3 |
| 35 | George Kirby | SEA | 62.0 | 5 | 3 | 0 | 0 | 52 | 16 | 2 | .249 | 6 | 3.45 | 19.0 |
| 36 | Emerson Hancock | SEA | 58.0 | 3 | 2 | 0 | 0 | 60 | 13 | 2 | .229 | 8 | 3.07 | 15.8 |
| 37 | Jacob deGrom | TEX | 50.0 | 3 | 3 | 0 | 0 | 61 | 8 | 0 | .201 | 10 | 3.02 | 15.6 |
| 38 | Drew Rasmussen | TB | 48.0 | 4 | 1 | 0 | 0 | 45 | 9 | 1 | .213 | 7 | 3.19 | 14.9 |
| 39 | Bailey Ober | MIN | 57.0 | 5 | 2 | 0 | 0 | 40 | 17 | 2 | .208 | 7 | 3.63 | 14.3 |
| 40 | Braxton Ashcraft | PIT | 55.0 | 2 | 2 | 0 | 0 | 56 | 14 | 3 | .222 | 5 | 3.09 | 14.2 |
| 41 | Foster Griffin | WSH | 56.0 | 5 | 2 | 0 | 0 | 54 | 18 | 4 | .225 | 10 | 4.02 | 13.7 |
| 42 | Bryan Woo | SEA | 59.0 | 4 | 2 | 0 | 0 | 55 | 12 | 2 | .213 | 6 | 3.51 | 13.7 |
| 43 | Michael Soroka | ARI | 49.0 | 6 | 2 | 0 | 0 | 55 | 14 | 3 | .266 | 4 | 3.49 | 13.5 |
| 44 | J.T. Ginn | ATH | 51.0 | 2 | 2 | 0 | 1 | 44 | 17 | 2 | .209 | 6 | 2.98 | 13.2 |
| 45 | Shota Imanaga | CHC | 58.0 | 4 | 4 | 0 | 0 | 61 | 16 | 0 | .206 | 7 | 3.38 | 13.1 |
| 46 | Joe Ryan | MIN | 56.0 | 3 | 3 | 0 | 0 | 61 | 14 | 3 | .199 | 3 | 3.02 | 12.9 |
| 47 | Mitch Keller | PIT | 58.0 | 4 | 2 | 0 | 0 | 41 | 16 | 2 | .216 | 4 | 3.86 | 12.4 |
| 48 | Martin Perez | ATL | 41.0 | 2 | 2 | 0 | 0 | 38 | 13 | 2 | .193 | 5 | 2.85 | 12.0 |
| 49 | Nolan McLean | NYM | 58.0 | 2 | 3 | 0 | 0 | 69 | 17 | 5 | .204 | 6 | 3.57 | 11.9 |
| 50 | Seth Lugo | KC | 58.0 | 1 | 4 | 0 | 0 | 51 | 21 | 0 | .275 | 2 | 3.68 | 11.3 |