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| MLB Pitching Leaders | |||||||||||||
| RK | PLAYER | TEAM | OPP | SCORE | IP | H | R | ER | BB | K | PIT | DEC | ESPN* |
| 1 | Cam Schlittler | NYY | @ TB | 5-1 W | 8.0 | 4 | 1 | 1 | 0 | 8 | 101 | W | 78.00 |
| 2 | Landen Roupp | SF | vs TOR | 10-1 W | 8.0 | 3 | 1 | 1 | 2 | 5 | 104 | W | 75.00 |
| 3 | Brandon Pfaadt | ARI | @ SD | 8-0 W | 5.0 | 4 | 0 | 0 | 0 | 6 | 72 | W | 65.00 |
| 4 | Dustin May | STL | vs MIL | 3-4 L | 4.2 | 4 | 0 | 0 | 0 | 7 | 81 | ND | 63.00 |
| 5 | Griffin Jax | TB | vs NYY | 1-5 L | 5.0 | 1 | 3 | 3 | 2 | 10 | 81 | L | 61.00 |
| 6 | Reynaldo Lopez | ATL | vs NYM | 6-7 L | 5.0 | 3 | 1 | 1 | 2 | 5 | 80 | ND | 60.00 |
| 7 | Noah Cameron | KC | vs PHI | 15-1 W | 5.0 | 6 | 1 | 1 | 5 | 7 | 105 | W | 53.00 |
| 8 | Shane Drohan | MIL | @ STL | 4-3 W | 6.0 | 6 | 3 | 1 | 2 | 2 | 85 | W | 52.00 |
| 9 | Freddy Peralta | NYM | @ ATL | 7-6 W | 4.2 | 6 | 3 | 1 | 1 | 6 | 103 | ND | 49.00 |
| Eric Lauer | LAD | vs COL | 8-7 W | 6.0 | 6 | 3 | 3 | 2 | 3 | 99 | ND | 49.00 | |
| 11 | Kevin Gausman | TOR | @ SF | 1-10 L | 5.1 | 5 | 7 | 4 | 5 | 8 | 92 | L | 39.00 |
| 12 | Walker Buehler | SD | vs ARI | 0-8 L | 5.0 | 7 | 7 | 7 | 1 | 4 | 93 | L | 28.00 |
| 13 | Miles Mikolas | WSH | vs HOU | 12-11 W | 6.0 | 9 | 7 | 7 | 2 | 3 | 99 | W | 27.00 |
| Kyle Freeland | COL | @ LAD | 7-8 L | 5.0 | 9 | 6 | 6 | 0 | 2 | 72 | ND | 27.00 | |
| 15 | Mike Burrows | HOU | @ WSH | 11-12 L | 4.1 | 9 | 10 | 7 | 2 | 3 | 83 | L | 12.00 |
| 16 | Cristopher Sanchez | PHI | @ KC | 1-15 L | 3.1 | 12 | 9 | 9 | 1 | 1 | 83 | L | .00 |