| NL - Pitching - ESPN Player Rating | ||||||||||||||
| RK | PLAYER | TEAM | IP | W | L | SV | BS | K | BB | HBP | BAA | HR | ERA | RAT |
| 1 | Jacob Misiorowski | MIL | 166.0 | 15 | 5 | 0 | 0 | 243 | 42 | 9 | .160 | 14 | 1.89 | 65.8 |
| 2 | Cristopher Sanchez | PHI | 193.0 | 17 | 6 | 0 | 0 | 215 | 44 | 6 | .258 | 17 | 2.93 | 60.8 |
| 3 | Yoshinobu Yamamoto | LAD | 179.0 | 14 | 8 | 0 | 0 | 178 | 41 | 6 | .180 | 19 | 2.51 | 58.5 |
| 4 | Jesus Luzardo | PHI | 178.0 | 14 | 5 | 0 | 0 | 221 | 52 | 11 | .215 | 15 | 2.87 | 56.9 |
| 5 | Chris Sale | ATL | 157.0 | 14 | 9 | 0 | 0 | 190 | 31 | 14 | .216 | 9 | 2.18 | 54.3 |
| 6 | Mason Miller | SD | 64.0 | 5 | 2 | 37 | 2 | 119 | 23 | 2 | .145 | 2 | 1.12 | 53.7 |
| 7 | Eduardo Rodriguez | ARI | 183.0 | 15 | 7 | 0 | 0 | 140 | 62 | 1 | .236 | 18 | 2.89 | 45.3 |
| 8 | Cade Cavalli | WSH | 169.0 | 13 | 5 | 0 | 0 | 200 | 48 | 16 | .232 | 18 | 3.02 | 42.4 |
| 9 | Chase Burns | CIN | 154.0 | 15 | 3 | 0 | 0 | 185 | 56 | 1 | .218 | 17 | 2.86 | 41.9 |
| 10 | Tarik Skubal | LAD | 146.0 | 10 | 7 | 0 | 0 | 173 | 25 | 5 | .214 | 13 | 2.70 | 39.5 |
| 11 | Zack Wheeler | PHI | 150.0 | 13 | 5 | 0 | 0 | 177 | 46 | 4 | .207 | 20 | 2.99 | 39.0 |
| 12 | Michael King | SD | 181.0 | 12 | 9 | 0 | 0 | 154 | 68 | 12 | .218 | 20 | 3.03 | 38.6 |
| 13 | Jhoan Duran | PHI | 56.0 | 2 | 6 | 32 | 2 | 79 | 9 | 4 | .226 | 2 | 1.76 | 33.9 |
| 14 | Max Meyer | MIA | 111.0 | 9 | 1 | 0 | 0 | 121 | 41 | 7 | .207 | 11 | 2.68 | 33.6 |
| 15 | Nolan McLean | NYM | 172.0 | 11 | 10 | 0 | 0 | 189 | 69 | 15 | .218 | 17 | 3.18 | 32.0 |
| 16 | Braxton Ashcraft | PIT | 165.0 | 14 | 6 | 0 | 0 | 173 | 35 | 7 | .235 | 22 | 3.65 | 27.7 |
| 17 | Trevor Megill | MIL | 58.0 | 3 | 3 | 28 | 3 | 66 | 15 | 1 | .185 | 1 | 2.76 | 27.6 |
| 18 | Robbie Ray | SD | 162.0 | 13 | 8 | 0 | 0 | 138 | 83 | 2 | .225 | 22 | 3.60 | 24.9 |
| 19 | Brandyn Garcia | ARI | 46.0 | 0 | 1 | 5 | 0 | 55 | 10 | 6 | .159 | 2 | 1.94 | 23.1 |
| 20 | Sandy Alcantara | MIA | 206.0 | 13 | 10 | 1 | 0 | 149 | 58 | 9 | .247 | 23 | 3.84 | 21.6 |
| 21 | Andre Pallante | STL | 151.0 | 12 | 7 | 0 | 0 | 104 | 47 | 6 | .250 | 11 | 3.70 | 21.2 |
| 22 | Mason Montgomery | PIT | 64.0 | 6 | 3 | 14 | 2 | 97 | 25 | 1 | .177 | 5 | 2.67 | 19.5 |
| 23 | Yuki Matsui | SD | 61.0 | 3 | 1 | 1 | 0 | 66 | 34 | 2 | .165 | 7 | 1.92 | 19.2 |
| 24 | Ben Brown | CHC | 68.0 | 4 | 2 | 1 | 1 | 65 | 19 | 2 | .186 | 2 | 1.85 | 18.3 |
| 25 | Tanner Scott | LAD | 60.0 | 1 | 6 | 22 | 4 | 77 | 14 | 1 | .212 | 4 | 2.82 | 17.3 |
| 26 | Raisel Iglesias | ATL | 57.0 | 1 | 2 | 33 | 3 | 60 | 17 | 1 | .223 | 6 | 2.68 | 17.1 |
| 27 | Grant Holmes | ATL | 141.0 | 9 | 5 | 0 | 0 | 110 | 59 | 3 | .235 | 20 | 3.49 | 16.8 |
| 28 | DL Hall | MIL | 56.0 | 3 | 0 | 0 | 1 | 59 | 33 | 1 | .151 | 5 | 2.09 | 16.5 |
| 29 | Martin Perez | ATL | 137.0 | 9 | 9 | 0 | 0 | 100 | 60 | 3 | .224 | 13 | 3.07 | 16.2 |
| 30 | Gordon Graceffo | STL | 77.0 | 8 | 1 | 1 | 2 | 58 | 33 | 3 | .182 | 5 | 2.56 | 15.6 |
| 31 | Riley O'Brien | STL | 62.0 | 3 | 9 | 37 | 8 | 62 | 29 | 10 | .230 | 5 | 4.21 | 14.4 |
| 32 | Didier Fuentes | ATL | 71.0 | 7 | 2 | 3 | 6 | 91 | 21 | 2 | .212 | 5 | 2.27 | 14.4 |
| 33 | Michael Soroka | ARI | 104.0 | 8 | 5 | 0 | 0 | 101 | 26 | 6 | .234 | 8 | 3.45 | 14.0 |
| 34 | Kyle Leahy | STL | 138.0 | 10 | 5 | 0 | 0 | 129 | 41 | 5 | .268 | 15 | 3.65 | 12.8 |
| 35 | Justin Wrobleski | LAD | 136.0 | 11 | 5 | 0 | 0 | 114 | 31 | 5 | .236 | 21 | 3.70 | 12.0 |
| 36 | Juan Morillo | ARI | 60.0 | 4 | 4 | 3 | 5 | 70 | 22 | 4 | .190 | 3 | 2.24 | 11.7 |
| 37 | Tyler Phillips | MIA | 122.0 | 5 | 6 | 2 | 1 | 99 | 52 | 3 | .236 | 17 | 3.45 | 10.8 |
| 38 | Alex Vesia | LAD | 54.0 | 2 | 1 | 3 | 2 | 67 | 31 | 0 | .156 | 4 | 2.83 | 10.8 |
| 39 | Shota Imanaga | CHC | 168.0 | 11 | 10 | 0 | 0 | 164 | 37 | 6 | .234 | 34 | 3.80 | 10.6 |
| 40 | Dylan Lee | ATL | 64.0 | 6 | 1 | 0 | 2 | 75 | 16 | 0 | .196 | 3 | 3.09 | 9.9 |
| 41 | Jonathan Loaisiga | ARI | 62.0 | 7 | 3 | 1 | 4 | 47 | 11 | 1 | .236 | 3 | 2.32 | 9.6 |
| 42 | Edgardo Henriquez | LAD | 60.0 | 4 | 1 | 2 | 1 | 71 | 25 | 6 | .177 | 1 | 2.85 | 9.6 |
| 43 | Bradgley Rodriguez | SD | 68.0 | 3 | 3 | 2 | 5 | 74 | 18 | 0 | .216 | 6 | 2.38 | 9.5 |
| 44 | Michael Petersen | MIA | 61.0 | 3 | 4 | 1 | 1 | 74 | 27 | 3 | .187 | 5 | 3.08 | 9.2 |
| 45 | Yohan Ramirez | PIT | 81.0 | 7 | 4 | 2 | 2 | 95 | 43 | 12 | .190 | 4 | 3.00 | 8.7 |
| 46 | Abner Uribe | MIL | 56.0 | 5 | 3 | 6 | 2 | 59 | 19 | 1 | .196 | 3 | 2.08 | 8.7 |
| 47 | Brock Burke | CIN | 72.0 | 6 | 5 | 2 | 1 | 73 | 39 | 4 | .201 | 5 | 2.36 | 8.4 |
| 48 | Adrian Morejon | SD | 82.0 | 9 | 3 | 3 | 5 | 101 | 24 | 5 | .208 | 4 | 2.85 | 7.8 |
| 49 | Paul Skenes | PIT | 168.0 | 10 | 11 | 0 | 0 | 192 | 47 | 11 | .230 | 19 | 3.91 | 7.8 |
| 50 | Kevin Gausman | CHC | 172.0 | 9 | 12 | 0 | 0 | 177 | 46 | 1 | .258 | 25 | 4.55 | 7.4 |