| Passing Leaders | |||||||||||
| PLAYER | TEAM | RESULT | COMP | ATT | YDS | TD | INT | SACK | FUM | RAT | |
Tyler Shough |
1. Tyler Shough, QB | NO | L 31-30 at DET | 35 | 56 | 410 | 3 | 2 | 5 | 1 | 87.7 |
| 2. Jordan Love, QB | GB | L 39-22 at MIN | 21 | 42 | 387 | 2 | 1 | 4 | 1 | 88.1 | |
| 3. Bryce Young, QB | CAR | L 59-37 vs. CHI | 23 | 37 | 361 | 3 | 1 | 2 | 0 | 110.3 | |
| 4. Josh Allen, QB | BUF | W 36-31 at HOU | 20 | 29 | 334 | 2 | 0 | 2 | 0 | 130.5 | |
| 5. Lamar Jackson, QB | BAL | W 41-23 at IND | 17 | 25 | 324 | 1 | 0 | 2 | 1 | 124.2 | |
| Rushing Leaders | ||||||||||
| PLAYER | TEAM | RESULT | CAR | YDS | AVG | TD | LNG | FUM | ||
Kenneth Walker III |
1. Kenneth Walker III, RB | KC | W 31-10 vs. DEN | 23 | 173 | 7.5 | 1 | 60 | 0 | |
| 2. Jahmyr Gibbs, RB | DET | W 31-30 vs. NO | 29 | 156 | 5.4 | 2 | 21 | 1 | ||
| 3. Derrick Henry, RB | BAL | W 41-23 at IND | 24 | 144 | 6.0 | 3 | 32 | 0 | ||
| 4. D'Andre Swift, RB | CHI | W 59-37 at CAR | 18 | 124 | 6.9 | 3 | 32 | 0 | ||
| 5. Breece Hall, RB | NYJ | W 23-10 at TEN | 22 | 102 | 4.6 | 1 | 13 | 0 | ||
| Receiving Leaders | ||||||||||
| PLAYER | TEAM | RESULT | REC | YDS | AVG | TD | LNG | FUM | ||
Chris Olave |
1. Chris Olave, WR | NO | L 31-30 at DET | 10 | 182 | 18.2 | 0 | 47 | 0 | |
| 2. Zay Flowers, WR | BAL | W 41-23 at IND | 5 | 150 | 30.0 | 1 | 54 | 0 | ||
| 3. Christian Watson, WR | GB | L 39-22 at MIN | 6 | 147 | 24.5 | 2 | 81 | 0 | ||
| 4. Jalen Coker, WR | CAR | L 59-37 vs. CHI | 8 | 138 | 17.3 | 2 | 51 | 0 | ||
| 5. Dalton Kincaid, TE | BUF | W 36-31 at HOU | 5 | 130 | 26.0 | 0 | 40 | 0 | ||
| Defensive Leaders | ||||||||||
| PLAYER | TEAM | RESULT | SOLO | AST | TOT | SACK | FF | INT | TD | |
Alex Singleton |
1. Alex Singleton, LB | DEN | L 31-10 at KC | 5 | 11 | 16 | 0.0 | 0 | 0 | 0 |
| 2. Anthony Hill Jr., LB | TEN | L 23-10 vs. NYJ | 2 | 14 | 16 | 0.0 | 0 | 0 | 0 | |
| 3. Jacob Rodriguez, LB | MIA | L 27-13 at LV | 5 | 9 | 14 | 0.0 | 0 | 0 | 0 | |
| 4. Devin Lloyd, LB | CAR | L 59-37 vs. CHI | 9 | 4 | 13 | 0.0 | 0 | 0 | 0 | |
| 5. Ernest Jones IV, LB | SEA | W 13-10 vs. NE | 8 | 5 | 13 | 0.0 | 0 | 0 | 0 | |