| Passing Leaders | |||||||||||
| PLAYER | TEAM | RESULT | COMP | ATT | YDS | TD | INT | SACK | FUM | RAT | |
Joe Burrow |
1. Joe Burrow, QB | CIN | L 22-17 vs. JAX | 39 | 54 | 428 | 1 | 2 | 2 | 0 | 86.0 |
| 2. Jared Goff, QB | DET | L 32-26 at CAR | 32 | 52 | 412 | 1 | 0 | 1 | 0 | 92.8 | |
| 3. Kirk Cousins, QB | LV | L 30-27 vs. KC | 31 | 52 | 365 | 2 | 1 | 0 | 0 | 85.8 | |
| 4. C.J. Stroud, QB | HOU | L 34-30 vs. DAL | 21 | 31 | 347 | 2 | 0 | 2 | 0 | 126.7 | |
| 5. Dak Prescott, QB | DAL | W 34-30 at HOU | 32 | 45 | 335 | 1 | 0 | 3 | 0 | 99.8 | |
| Rushing Leaders | ||||||||||
| PLAYER | TEAM | RESULT | CAR | YDS | AVG | TD | LNG | FUM | ||
Kenneth Walker III |
1. Kenneth Walker III, RB | KC | W 30-27 at LV | 22 | 177 | 8.0 | 2 | 76 | 0 | |
| 2. Kyle Monangai, RB | CHI | W 23-12 vs. NYJ | 30 | 146 | 4.9 | 2 | 26 | 0 | ||
| 3. Bijan Robinson, RB | ATL | W 45-24 at NO | 19 | 145 | 7.6 | 2 | 59 | 0 | ||
| 4. Chuba Hubbard, RB | CAR | W 32-26 vs. DET | 20 | 122 | 6.1 | 2 | 32 | 0 | ||
| 5. Ollie Gordon II, RB | MIA | L 15-10 at MIN | 9 | 100 | 11.1 | 1 | 53 | 0 | ||
| Receiving Leaders | ||||||||||
| PLAYER | TEAM | RESULT | REC | YDS | AVG | TD | LNG | FUM | ||
Tetairoa McMillan |
1. Tetairoa McMillan, WR | CAR | W 32-26 vs. DET | 14 | 192 | 13.7 | 2 | 32 | 0 | |
| 2. CeeDee Lamb, WR | DAL | W 34-30 at HOU | 17 | 189 | 11.1 | 1 | 30 | 0 | ||
| 3. Tee Higgins, WR | CIN | L 22-17 vs. JAX | 11 | 157 | 14.3 | 0 | 26 | 0 | ||
| 4. Carnell Tate, WR | TEN | L 24-18 at BAL | 9 | 145 | 16.1 | 0 | 33 | 1 | ||
| 5. Puka Nacua, WR | LAR | W 24-20 at PHI | 9 | 125 | 13.9 | 0 | 32 | 0 | ||
| Defensive Leaders | ||||||||||
| PLAYER | TEAM | RESULT | SOLO | AST | TOT | SACK | FF | INT | TD | |
Jacob Rodriguez |
1. Jacob Rodriguez, LB | MIA | L 15-10 at MIN | 9 | 9 | 18 | 0.0 | 0 | 0 | 0 |
| 2. Minkah Fitzpatrick, S | NYJ | L 23-12 at CHI | 8 | 8 | 16 | 0.0 | 0 | 1 | 0 | |
| 3. Jeremiah Trotter Jr., LB | PHI | L 24-20 vs. LAR | 10 | 5 | 15 | 0.0 | 0 | 0 | 0 | |
| 4. Alex Singleton, LB | DEN | L 24-14 at SF | 7 | 7 | 14 | 0.0 | 0 | 0 | 0 | |
| 5. Dane Belton, S | NYJ | L 23-12 at CHI | 6 | 8 | 14 | 0.0 | 0 | 0 | 0 | |