| Passing Leaders | |||||||||||
| PLAYER | TEAM | RESULT | COMP | ATT | YDS | TD | INT | SACK | FUM | RAT | |
Aaron Rodgers |
1. Aaron Rodgers, QB | GB | W 42-24 vs. LV | 25 | 31 | 429 | 5 | 0 | 1 | 0 | 158.3 |
| 2. Matthew Stafford, QB | DET | L 42-30 vs. MIN | 30 | 45 | 364 | 4 | 1 | 2 | 0 | 111.7 | |
| 3. Kirk Cousins, QB | MIN | W 42-30 at DET | 24 | 34 | 338 | 4 | 0 | 0 | 0 | 141.5 | |
| 4. Philip Rivers, QB | LAC | L 23-20 at TEN | 24 | 38 | 329 | 2 | 0 | 1 | 0 | 108.3 | |
| 5. Jacoby Brissett, QB | IND | W 30-23 vs. HOU | 26 | 39 | 326 | 4 | 0 | 1 | 1 | 126.7 | |
| Rushing Leaders | ||||||||||
| PLAYER | TEAM | RESULT | CAR | YDS | AVG | TD | LNG | FUM | ||
Dalvin Cook |
1. Dalvin Cook, RB | MIN | W 42-30 at DET | 25 | 142 | 5.7 | 2 | 23 | 0 | |
| 2. Leonard Fournette, RB | JAX | W 27-17 at CIN | 29 | 131 | 4.5 | 0 | 20 | 0 | ||
| 3. Chase Edmonds, RB | ARI | W 27-21 at NYG | 27 | 126 | 4.7 | 3 | 22 | 0 | ||
| 4. Josh Jacobs, RB | LV | L 42-24 at GB | 21 | 124 | 5.9 | 0 | 42 | 0 | ||
| 5. Latavius Murray, WR | NO | W 36-25 at CHI | 27 | 119 | 4.4 | 2 | 17 | 0 | ||
| Receiving Leaders | ||||||||||
| PLAYER | TEAM | RESULT | REC | YDS | AVG | TD | LNG | FUM | ||
Stefon Diggs |
1. Stefon Diggs, WR | MIN | W 42-30 at DET | 7 | 143 | 20.4 | 0 | 66 | 0 | |
| 2. Alex Erickson, WR | CIN | L 27-17 vs. JAX | 8 | 137 | 17.1 | 0 | 48 | 0 | ||
| 3. Marquez Valdes-Scantling, WR | GB | W 42-24 vs. LV | 2 | 133 | 66.5 | 1 | 74 | 0 | ||
| 4. Michael Thomas, WR | NO | W 36-25 at CHI | 9 | 131 | 14.6 | 0 | 34 | 0 | ||
| 5. Darren Waller, TE | LV | L 42-24 at GB | 7 | 126 | 18.0 | 2 | 48 | 0 | ||
| Defensive Leaders | ||||||||||
| PLAYER | TEAM | RESULT | SOLO | AST | TOT | SACK | FF | INT | TD | |
Blake Martinez |
1. Blake Martinez, LB | GB | W 42-24 vs. LV | 8 | 8 | 16 | 0.0 | 1 | 0 | 0 |
| 2. Bobby Wagner, LB | SEA | L 30-16 vs. BAL | 7 | 6 | 13 | 0.0 | 1 | 0 | 0 | |
| 3. Jessie Bates III, S | CIN | L 27-17 vs. JAX | 8 | 4 | 12 | 0.0 | 0 | 0 | 0 | |
| 4. Eric Kendricks, LB | MIN | W 42-30 at DET | 6 | 6 | 12 | 0.0 | 0 | 0 | 0 | |
| 5. Deion Jones, LB | ATL | L 37-10 vs. LAR | 8 | 3 | 11 | 0.0 | 0 | 0 | 0 | |