| Passing Leaders | |||||||||||
| PLAYER | TEAM | RESULT | COMP | ATT | YDS | TD | INT | SACK | FUM | RAT | |
Jared Goff |
1. Jared Goff, QB | LAR | L 55-40 vs. TB | 45 | 68 | 517 | 2 | 3 | 2 | 1 | 80.3 |
| 2. Aaron Rodgers, QB | GB | L 34-27 vs. PHI | 34 | 53 | 422 | 2 | 1 | 1 | 1 | 93.4 | |
| 3. Matt Ryan, QB | ATL | L 24-10 vs. TEN | 35 | 53 | 397 | 0 | 0 | 5 | 1 | 88.3 | |
| 4. Jameis Winston, QB | TB | W 55-40 at LAR | 28 | 41 | 385 | 4 | 1 | 2 | 0 | 120.5 | |
| 5. Baker Mayfield, QB | CLE | W 40-25 at BAL | 20 | 30 | 342 | 1 | 1 | 1 | 0 | 102.4 | |
| Rushing Leaders | ||||||||||
| PLAYER | TEAM | RESULT | CAR | YDS | AVG | TD | LNG | FUM | ||
Leonard Fournette |
1. Leonard Fournette, RB | JAX | W 26-24 at DEN | 29 | 225 | 7.8 | 0 | 81 | 0 | |
| 2. Nick Chubb, RB | CLE | W 40-25 at BAL | 20 | 165 | 8.3 | 3 | 88 | 0 | ||
| 3. Kerryon Johnson, RB | DET | L 34-30 vs. KC | 26 | 125 | 4.8 | 0 | 14 | 1 | ||
| 4. Frank Gore, RB | BUF | L 16-10 vs. NE | 17 | 109 | 6.4 | 0 | 41 | 0 | ||
| 5. Chris Carson, RB | SEA | W 27-10 at ARI | 22 | 104 | 4.7 | 0 | 12 | 0 | ||
| Receiving Leaders | ||||||||||
| PLAYER | TEAM | RESULT | REC | YDS | AVG | TD | LNG | FUM | ||
Davante Adams |
1. Davante Adams, WR | GB | L 34-27 vs. PHI | 10 | 180 | 18.0 | 0 | 58 | 0 | |
| 2. Chris Godwin Jr., WR | TB | W 55-40 at LAR | 12 | 172 | 14.3 | 2 | 30 | 0 | ||
| 3. Jarvis Landry, WR | CLE | W 40-25 at BAL | 8 | 167 | 20.9 | 0 | 65 | 0 | ||
| 4. Robert Woods, WR | LAR | L 55-40 vs. TB | 13 | 164 | 12.6 | 0 | 37 | 0 | ||
| 5. Austin Hooper, TE | ATL | L 24-10 vs. TEN | 9 | 130 | 14.4 | 0 | 28 | 0 | ||
| Defensive Leaders | ||||||||||
| PLAYER | TEAM | RESULT | SOLO | AST | TOT | SACK | FF | INT | TD | |
De'Vondre Campbell |
1. De'Vondre Campbell, LB | ATL | L 24-10 vs. TEN | 7 | 10 | 17 | 0.0 | 2 | 0 | 0 |
| 2. Joe Schobert, LB | CLE | W 40-25 at BAL | 9 | 7 | 16 | 1.0 | 0 | 0 | 0 | |
| 3. Eric Weddle, S | LAR | L 55-40 vs. TB | 10 | 5 | 15 | 0.0 | 0 | 0 | 0 | |
| 4. Blake Martinez, LB | GB | L 34-27 vs. PHI | 10 | 5 | 15 | 0.0 | 0 | 0 | 0 | |
| 5. Zach Cunningham, LB | HOU | L 16-10 vs. CAR | 8 | 6 | 14 | 0.0 | 0 | 0 | 0 | |