| Passing Leaders | |||||||||||
| PLAYER | TEAM | RESULT | COMP | ATT | YDS | TD | INT | SACK | FUM | RAT | |
Aaron Rodgers |
1. Aaron Rodgers, QB | GB | L 34-31 at MIN | 23 | 33 | 385 | 4 | 0 | 2 | 0 | 148.4 |
| 2. Justin Herbert, QB | LAC | W 41-37 vs. PIT | 30 | 41 | 382 | 3 | 1 | 2 | 0 | 116.1 | |
| 3. Kirk Cousins, QB | MIN | W 34-31 vs. GB | 24 | 35 | 341 | 3 | 0 | 2 | 0 | 128.4 | |
| 4. Colt McCoy, WR | ARI | W 23-13 at SEA | 35 | 44 | 328 | 2 | 0 | 2 | 0 | 112.9 | |
| 5. Ryan Tannehill, QB | TEN | L 22-13 vs. HOU | 35 | 52 | 323 | 1 | 4 | 2 | 0 | 58.4 | |
| Rushing Leaders | ||||||||||
| PLAYER | TEAM | RESULT | CAR | YDS | AVG | TD | LNG | FUM | ||
Jonathan Taylor |
1. Jonathan Taylor, RB | IND | W 41-15 at BUF | 32 | 185 | 5.8 | 4 | 40 | 0 | |
| 2. D'Andre Swift, RB | DET | L 13-10 at CLE | 14 | 136 | 9.7 | 1 | 57 | 0 | ||
| 3. Nick Chubb, RB | CLE | W 13-10 vs. DET | 22 | 130 | 5.9 | 0 | 15 | 0 | ||
| 4. Joe Mixon, RB | CIN | W 32-13 at LV | 30 | 123 | 4.1 | 2 | 20 | 0 | ||
| 5. Antonio Gibson, RB | WSH | W 27-21 at CAR | 19 | 95 | 5.0 | 0 | 20 | 1 | ||
| Receiving Leaders | ||||||||||
| PLAYER | TEAM | RESULT | REC | YDS | AVG | TD | LNG | FUM | ||
Justin Jefferson |
1. Justin Jefferson, WR | MIN | W 34-31 vs. GB | 8 | 169 | 21.1 | 2 | 56 | 0 | |
| 2. Elijah Moore, WR | NYJ | L 24-17 vs. MIA | 8 | 141 | 17.6 | 1 | 62 | 0 | ||
| 3. Marquez Valdes-Scantling, WR | GB | L 34-31 at MIN | 4 | 123 | 30.8 | 1 | 75 | 0 | ||
| 4. Darnell Mooney, WR | CHI | L 16-13 vs. BAL | 5 | 121 | 24.2 | 1 | 60 | 0 | ||
| 5. Darren Waller, TE | LV | L 32-13 vs. CIN | 7 | 116 | 16.6 | 0 | 31 | 0 | ||
| Defensive Leaders | ||||||||||
| PLAYER | TEAM | RESULT | SOLO | AST | TOT | SACK | FF | INT | TD | |
Roquan Smith |
1. Roquan Smith, LB | CHI | L 16-13 vs. BAL | 13 | 4 | 17 | 0.0 | 0 | 0 | 0 |
| 2. Jordyn Brooks, LB | SEA | L 23-13 vs. ARI | 11 | 4 | 15 | 0.0 | 0 | 0 | 0 | |
| 3. Quincy Williams, LB | NYJ | L 24-17 vs. MIA | 10 | 5 | 15 | 0.0 | 0 | 0 | 0 | |
| 4. Jayon Brown, LB | TEN | L 22-13 vs. HOU | 6 | 8 | 14 | 0.0 | 0 | 0 | 0 | |
| 5. Jeremy Chinn, S | CAR | L 27-21 vs. WSH | 9 | 4 | 13 | 0.0 | 0 | 0 | 0 | |